Staphylococcal Scalded Skin Syndrome in Neonates and Children Essay

Staphylococcal Scalded Skin Syndrome in Neonates and Children - Essay ExampleSSSS is caused by the release of dickens exotoxins (epidermolytic toxins A and B) from toxigenic strains of the bacteria (or a germ) Staphylococcus aureus. Desmosomes ar the part of the skin cell responsible for adhering to the adjacent skin cell. The toxins bind to a molecule within the desmosome called Desmoglein 1 and break it up so the skin cells become unstuck, reports Staphylococcal scalded skin syndrome (2006).SSSS dissolve be detected by a fever, redness that has spread on the skin, and irritability. Fluid-filled blisters, which rupture easily, appear within 24-48 hours of the fever and widespread redness of the skin. After the blisters rupture, the skin looks like it has been scalded, or burned. Approximately 15-40% of sizable individuals are carriers of Staphylococcus aureus and as carriers, they carry the bacteria but no signs of the disease or symptoms are revealed. These carriers introduce t he Staphylococcus aureus (without any sign of transmittance or disease) into the childcare facility. But these individuals, particularly infants, get SSSS from a localised staphylococcal infection, which is the producer of the two exotoxins (epidermolytic toxins A and B) and outbreaks can often be effect occurring in facilities that provide childcare. The reason olderchildren and adults commonly do not get SSSS is because throughout a lifetime, immunities are built. In children younger than the age of quintette (especially infants), there is a lack of immunity built up that can defend against the toxin. Also, toxins are removed from the body via the kidneys due to the immature renal clearance system. These are the reasons why infants are more at risk. (Staphylococcal scalded skin syndrome, 2006).Diagnosing SSSS can be as simple as looking at the style of the skin. Skin tissue can be examined with a microscope. The bacteria can be found by examining surface fluid or pus. Blood c an be tested for the SSSS infection. (Staphylococcal Scalded Skin Syndrome, 2006.) Pathophysiology has revealed a connection with other complications. For example, staphylococcus aureus causes the autoantibodies and bullous impetigo, a generalized form of SSS, which in turn causes pemphigus. Pemphigus was known to be misrelated to the other conditions. However, a study by Stanley and Amagai (2006) of the molecular pathophysiology of pemphigus revealed that the molecular pathophysiology contributes to the mechanism of the formation of blisters in bullous impetigo and the staphylococcal scalded-skin syndrome. Stanley and Amagai (2006) report the followingStaphylococcal skin infections are among the most common skin diseases in children. Classic studies more than 30 years ago showed that the blisters in bullous impetigo and the scalded-skin syndrome are caused by exfoliative toxin released by staphylococcusSubsequently, it was discovered that two major serotypes of this toxin, A and B , cause bullous impetigo and the scalded-skin syndrome in cases of the scalded-skin syndrome, it circulates throughout the body, causing blisters at sites Staphylococcal Scalded Skin Syndrome 4distant from the infection.49 The risk of death from the