Tuesday, June 4, 2019

Does Malaysia Need The Green Belt Concept Environmental Sciences Essay

Does Malaysia Need The Green Belt Concept Environmental Sciences analyzeMalaysia is moving forward to be an industrialized economy. Malaysia motivated from material production to manufacturing. The Malaysia manufacturing sector contributed 32% of the gross domestic product (GDP) in 2007, exports of manufactured products chronicle for 75% of Malaysias total export in 2007. The manufacturing industries bewilder become the economys main source of appendage in recent years.According to the Third industrial Masterplan (IMP3) 2006 2020, 12 industries in the manufacturing sector have been targeted for further information and promotion (Table 1). These industries argon strategically important in contributing to the greater growth of the manufacturing sector, in damage of higher value-added, technology, exports, knowledge content, multiplier and spin-off effects and potential to be integrated regionally and globally. But, on the other side, the hereafter target might likewise encour age environmental degradation if there is no comprehensive plan toward sustainable industrial development is taken into consideration.Table 1 Exports and Investments Targets for the 12 Targeted Manufacturing Industries cum Ministry of International Trade and IndustryEnvironmental protection through contamination prevention and the meeting of environmental standards by waste treatment of the effluents in the variant industries have not worked in many countries. The problem of industrial environmental taint is actuateicularly serious in under create countries where the enforcement of environmental regulations is not stringently enforced. Malaysia can experience high chances of interdict environmental impacts due to its efforts to boost the rapid industrialisation of its economy. Many aspects of the residential environment and alive conditions of houses located intimately industrial atomic number 18as potentially affected.Evidence shows that plants can reduce the taint le vel. In develop nation they have come out with a putting surfaceway excogitate to buffer the urban and industrial area from spreading its pollutants. A greenway is an area of husbandry that is go ond for a non-urban drop use. The term of greenbelts tend to helping two features, an open shore upscape (green) and a linear shape (belt). All this while, greenbelt was not being strongly addressed on developing country due to its target on economic growth.Develop country like United Kingdom and Canada have come out with their own greenbelt Plan. greenbelts in the UK have had a profound effect on the landscape around urban areas, for the most part achieving their purposes of keeping the countryside open and preventing new development provided for agribusiness, forestry and recreation. The London Green Belt was created in response to the unchecked and sprawling growth that took place in that urban center during the 1920s and 1930s.1.2 Issues and Problems StatementRapid industri alisation can have a detrimental effect on the environment which is related to several including resource use, wet and air pollution as s closely as waste generation. The severity of these environmental consequences whitethorn vary, depending on the technologies used in the industrial production process and its organization.Malaysias rapid economic and industrial growth is characterized as a mixed-use urban areas development that incorpo place residential industrial areas. These residential areas support the industry by providing them clement resources. This growth produces both positive and negative impacts on housing development. The lack of usable arable land for urban development further results in some housing estates being nestled at bottom industrial mental hospitals as consequences to urban sprawl. authoritative status of green efforts in Malaysia is counseling on commanding and controlling the wastes occurring during the manufacturing stage of a product. In Malaysia, however big businesses have committed to voluntary initiatives towards green industrial development and this approach is yet to be accepted by SMEs ( runty and medium enterprise).Landscaping the industrial areas by the development of greenbelts is an effective way of mitigating industrial pollution.The effectiveness of green belts differs depending on location and operation. They are often being eroded by urban rural fringe use and sometimes, development encroached over the green belt area, resulting in the creation of satellite townspeoples which, although separated from the city by green belt, operation more like suburbs than independent communities.1.3 Objectives of Studyi) To clarify the importance of industrial greenbelt for economic growth whilst minimizing environmental degradation.ii) To identify the significant aspect that should be considered for green industrial development.iii) To give a recommendation for effective strategies of Greenbelts Plan for industrials area towards achieving sustainable industrial development.1.4 Significance of StudyGreenbelts in urban areas exceptionally in industrial are important to the ecological health of any given region. The respective(a) plants and trees in greenbelts serve as organic sponges for various get ups of pollution, and as carbon sequestration to help offset global warming. On the other get through, industrial activities in urban areas have caused cities to maintain higher temperatures than their surrounding countryside and these phenomena is cognize as an urban heat island. Parks and greenbelts will reduce temperatures while the Central Business District (CBD), commercial areas, and even suburban housing tracts are areas of warmer temperatures.Greenbelts are also important to help urban dwellers feel more connected to nature. All cities should earmark certain areas for the development of greenbelts to bring feel and colour to the concrete jungle and serving a healthy environment to the urban ities. The future risk from rapid expanding of industrial development should be investigate and must(prenominal) be seriously taken into consideration. Therefore, through the establishment of planned greenbelts it can helps in limiting urban sprawl.2.0 EVOLUTION OF GREENBELT CONCEPT2.1 History of Greenbelt ConceptThe thinker of greenbelt was inspired by Sir Ebenezer Howard, a British social reformer, at the beginning of the twentieth century. Howard proposed Garden City which would not that be free of pollution but would also be antidote of polluted cities. The garden cities would be surrounded by a green background knowledge of agricultural land providing local employment opportunities as well as open space for recreation. It was British architect and planner Raymond Unwin, a town interior decorator and contemporary of Howards, who coined the term greenbelt (Ruth and William, 1994). In 1898 the concept was positive to tackle the problems associated with the planning of new to wns located outside the periphery of London, which was then sprawling furthest into the countryside.The Garden City Concept is 1 out of many attempts to reduce and solve social problems during the industrialisation Period. The problems occurred, as more and more farmers became workers in the factories. The living conditions became worse, due to the fact that many workers settlements were located next to the industrial areas or within the cities. plan 1 illustrates diagram of The Three Magnets where Howard analysed why people move to city or to the country side. Howards proposal emphasized the integration of the town, the country. He found out that both have advantages and utilisation as magnets. He started with discussions of the optimum size for towns whereby a central city of 58,000 people surrounded by smaller garden cities of 30,000 people each (Figure 2). Green space or greenbelt and agricultural land will be as study component in the garden city whereby the permanent gree n space would separate the city and towns and serving as a horizontal fence of farmland. The requirement of the greenbelt or agricultural land for the Garden City in Howards view was 5,000 farming of the total 6,000 acres.Therefore, his solution was to develop a city structure which contains the advantages of a city and those of the countryside. The main objective of the concept is to found a new city.Figure 2 Ebenezer Howard, Garden City.Figure 1 Garden Cities of To-morrow The Three Magnets, Ebenezer Howard, 1902In the United States, Franklin Roosevelt tried to adapt Howards new town concept as part of its resettlement program. In the American concept of greenbelt, relatively wide band of rural land or open space surrounded a town or city. The term greenbelt meant, loosely, any swath of open space separating or interrupting urban development. The designated land is controlled through regulation or public or quasi-public ownership (such as the Nature Conservancy) to retain its natu ral character and provide a resemblance of rural ambience in urban areas (Ruth and William, 1994).2.2 A Greenbelt as a Development Plan ComponentA greenbelt is a policy and land use designation used in land use planning to retain areas of largely undeveloped, wild, or agricultural land surrounding or neighbouring urban areas. Similar concepts are greenways or green wedges which have a linear character and may run through an urban area instead of around it. In essence, a green belt is an imperceptible line encircling a certain area, preventing development of the area allowing wildlife to return and be established.The green belt policy was pioneered in the United Kingdom in the 1930s after pressure from the Campaign to Protect Rural England (CPRE) and various other organizations. There are fourteen green belt areas, in the UK masking piece 16,716 km, or 13% of England, and 164 km of Scotland In United Kingdom town planning, the green belt is a policy for controlling urban growth. Th e idea is for a ring of countryside where urbanisation will be resisted for the foreseeable future, maintaining an area where agriculture, forestry and outdoor leisure can be expected to prevail. The fundamental aim of green belt policy is to prevent urban sprawl by keeping land permanently open, and consequently the most important attribute of green belts is their openness.2.2 Categories of GreenbeltA greenbelt principal purpose is to protect open space for natural, cultural, or scenic resources, to separate urban communities, to preserve and conserve natural resources and agriculture. Therefore, greenbelt can be categorized as below.Figure 3 Category of Greenbelt2.2.1 Shelter Belts and Wind BreaksA shelterbelt is usually a roadblock longer than a wind break and consists of a combination of shrubs and trees intended for the protection of field crops and the conservation of soil and water. A wind break is a barrier for protection from winds commonly associated with vegetable gardens and orchards. (Abbasi and Khan, 2000)The objectives of creating shelterbelts areto protect agricultural landto shelter population in a city-from hot wind antiaircraftto arrest particulate matter matters as much as possibleto shelter live-stockto control sand movementto provide healthy habitat2.2.1 timberland BeltsForest belts is consists of protected natural forest. The objectives of preserving forest belts areto protect watershed areato protect wildlife and its habitatto act as major carbon sequestrationto preserve the exotic and indigenous species of forest vegetationto achieve environmental equilibrium with development2.3 Greenbelt Encroachment by UrbanisationThere is no doubtfulness that human civilisation has had a negative impact on biodiversity and since the industrial revolution the negative impacts have only increased with processes such as over fishing and hunting, agriculture, the use of herbicides and pesticides and urban sprawl (Hunter, 2007).Rapid urban growth has led to the problems of urban sprawl, ribbon development, unregulated development, high cost for urban infrastructure, and pollution due to the inadequate giving medication of urban and industrial waste. All such issues involve land. Land can be used for agriculture, forestry, grazing, industrial and urban uses, public-service corporation corridors, roads, waste disposal and recreation. With the increase of urban population, more and more green areas have to be converted into urban use.Large cities on the other hand need to have the land to spread out. Increase in population will put the pressure on land to serve a reveal accommodation and facilities for human needs. industrial development will provide job for people, but in the same time it provides an opportunity to the developer to clear up the land for housing development. When there is housing development, other kind of development will follows, such as commercial retail areas and school.3.0 THE GROWTH OF INDUSTRIAL ESTATE3. 1 Industrialization EvolutionEver since Industrial Revolution from late eighteen century, economic progress and development have been closely identified with industrialization. This thinking has continued to charm policy makers especially so in developing countries (Jomo, 1993). Since the early 1970s, it has been widely recognized that to ease the problems of poverty and mass unemployment encountered in developing countries, industrialization should mutant a key role in the economic growth of these nations.The types of industries deemed most suitable for promotion in developing countries are the small and medium-scale industries. These industries are generally less capital intensive than large-scale industries and hence are more spread out in terms of ownership. Establishment of small and medium-scale industries could thus runway to a more equitable distribution of income. Former studies on development of small-scale industries have concluded that an effective means of promoting the growth and dispersal of small and medium-scale industries is the provision of proper sites for the establishment of these enterprises. These sites should preferably be located in an industrial estate which is defined as a tract of land which is subdivided and developed according to a comprehensive plan for use of a community of industrial enterprises (Fong 1980). In other words, an industrial estate can also be known as an industrial park.An industrial park is defined as a large tract of land, sub-divided and developed for the use of several firms simultaneously, distinguished by its shareable infrastructure and close proximity of firms. Types and synonyms of industrial parks include industrial estates, industrial districts, export processing zones, industrial clusters, business parks, office parks, science and look into parks, bio-technology parks and eco-industrial park (Peddle, 1993).3.2 Industrial Estate Development in MalaysiaFigure 4 Malaysias Industrial Development Phase (1867 1957)Export of agricultural products minerals(1957 1969)Import exchange Industrialization Strategy (ISI)(1970 1980)Export Oriented Industrialization Strategy (EOI)(1981 1986)Import substitute Industrialization Strategy (ISI)(1987 1996)Export Oriented Industrialization Strategy (EOI)(1997 2005)retrieval Period(EOI)Phase 1Phase 2Phase 3Phase 4Phase 5Phase 6(2006 beyond)EOIPhase 7Malaysias industrial development can be classified into seven var.s according to industrial strategies (Figure 4). The first bod was during the British colonial rule (1867-1957) which was largely peculiar(a) to export of agricultural products and minerals mainly rubber and tin. The period immediately after independence (1957-1969) is the second phase largely dominated by the Import Substitution Industrialization strategy (ISI). Export Oriented Industrialization strategy (EOI) was introduced in 1970 until 1980, followed by the second round of ISI from 1981 up to 1986, an constitute the third and fourth phase respectively. The fifth phase marked the return to EOI in 1987 till 1996. The Asian crisis and the recovery period constitute another phase from 1997 up until 2005. The final phase was in 2006 and beyond where Malaysian economy hopes to move towards global competitiveness.In early 1970s it has been realized that rapid economic development in developing countries leads to an acute ine smell in income distribution. To prevent massive dissatisfaction among their citizens, developing countries were urged to achieve economic growth (particularly industrial growth) with distribution of income as their development goal.Malaysia is one of the scurrying growing economies in the world and in many ways a Third World success story. From a country dependent on agriculture and primary commodities in the sixties, Malaysia has today become an export driven economy spurred on by high technology, knowledge based and capital intensive industries.The establishment of industrial estate s in the locations where such activities are desired became a good way of promoting growth and dispersal of industrial activities which can accelerate the economy of the country. Industrial estates are specific areas zoned for industrial activity where infrastructure (such as roads, power and other utility services) is provided to facilitate the growth of industries and to minimize the impacts on the environment.Industrial estates may include effluent treatment unfluctuating and toxic waste collection, treatment, and disposal air pollution and effluent monitoring technical services on pollution prevention quality management (quality assurance and control) and laboratory services.In the context of economic strategy, State frugal Development Corporations (SEDCs) were established by the various Malaysian states to stimulate industrialization through the development of industrial estates in the respective states. The industrial estates to be established by these SEDCs are envisaged to be in the form of improved tracts of land, with access roads and utility services. Industrial land so developed are leased out (usually for 99 years) to interested entrepreneurs. The lower rates are for industrial land developed in the rural areas, while the higher rates are for such land developed in the urban areas.Currently, Malaysia has over 200 industrial estates or parks occupying a total of 16,000 hectares and 13 Free Industrial Zones (FIZs) developed by government agencies, namely, the State Economic Development Corporations (SEDCs), Regional Development Authorities (RDAs), port authorities and municipalities throughout the country.New sites, fully equipped with infrastructure facilities such as roads, electricity and water supplies, and telecommunications, are continuously being developed by state governments as well as private developers to meet demand. Specialised parks have been developed in Malaysia to run to the needs of specific industries. Examples of these parks a re the Technology Park Malaysia in Bukit Jalil, Kuala Lumpur and the Kulim Hi-Tech Park in the northern state of Kedah which cater to technology-intensive industries and RD activities.3.3 Environmental Impacts from the Industrial EstatesThe effects on the environment connected with industrial activities are mainly related to the production of industrial wastes either from its sacking or effluent discharges. Figure 5 illustrates on the possible environmental impacts of industrial estates.POSSIBLE ENVIRONMENTAL IMPACT OF INDUSTRIAL ESTATESSpillsContaminated soil lost future land useDisposal of solid wastesLocal nuisances such as ring, lighting transportLandscape disturbanceOzone depleting greenhouse gasesHabitat degradation air PollutionFreshwater PollutionMarine PollutionRisks from hazardous wasteExposure to toxic chemicalsFigure 5 Possible environmental impacts of industrial estatesIndustrial development may always cause changes to the physical environment. Under natural condit ion, landuse changes can be absorbed by the physical environment through interactions of the various components to attain a dynamic equilibrium state. Rapid human disturbance will create imbalance to the environmental ecosystem as well as to human quality of life. There are a number of forms of industrial pollution. One of the most common is water pollution, caused by dumping of industrial waste into waterways, or improper containment of waste, which causes leakage into groundwater and waterways. Industries release pollutants which impact air quality that lead to photochemical smog, haze and acidification. Due to industrial discharges, and the indiscriminate disposal of raw materials, land pollution takes place. Both, air and water pollution will affected human beings, birds and aquatic life.Ozone depletion is another result of industrial pollution. Chemicals released by industries will affect the stratosphere, one of the atmospheric layers surrounding earth. The ozone layer in the stratosphere protects the earth from harmful ultraviolet radiation from the sun. The emission from industries will removes some of the ozone, causing holes to open up in this layer and allowing the radiation to reach the earth. Ultraviolet radiation is known to cause skin cancer and has damaging effects on plants and wildlife.Activities in industrial estates also can cause noise pollution. Industrial noise refers to noise that is created in the factories which is jarring and unbearable. Sound becomes noise only it becomes unwanted and when it becomes more than that it is referred to as noise pollution. Heavy industries like shipbuilding and iron and steel have long been associated with Noise Induced Hearing Loss (NIHL). Continuous exposure to noise pollution leads to hearing impairment especially for people who are working in the industry and common people as well. It has been scientifically proved that noise more than 85 decibels can cause hearing impairment and does not meet the s tandards set for healthy working environment.4.0 A RATIONALE FOR AN INDUSTRIAL GREENBELT4.1 Current Status of Greenbelt Consideration in Industrial EstateAs highlight in earlier chapter, current status of green efforts in Malaysia is focusing on commanding and controlling the wastes produce during the manufacturing stage of a product. Green efforts in Malaysia can be classified into four groups as followsBroad maneuver Principles Establishing common principles and statements of intent across subscribing organizations.Process Based Management Systems ISO 14001 is a well known example of a process based environmental management system.Performance Based Systems Public disclosure of industrial pollution programs is examples of voluntary programs with clear performance standards.Process-based Systems with Performance Elements Establishing a hybrid system that combines a incorporated management system approach with specific performance requirements.Unfortunately, there is no specific gu ideline and regulation of creating and preserving greenbelt in developing industrial estates as many parties seen it as a secondly important factor. In Malaysia, Kulim Hi-Tech Park is the first in country that can be seen as well planned fully-integrated high technology park. Besides providing one of the best infrastructures, the Parks Masterplan also emphasizes on the quality of life within a self-contained township. conveniences incorporated in the plan include a shopping centre, a hospital, educational institutions and recreational facilities. But still, we are lacking in controlling the development over-exploitation the land resulting which can resulting environmental deterioration.4.2 Pollution Status Caused by Industrial in MalaysiaThe two major environmental issues in Malaysia caused by industrial activities are atmospheric pollution and solid and hazardous wastes (Khidir and Suhaiza, 2009).4.2.1 Atmospheric PollutionAtmospheric pollution has long been associated with the bu rning of fossil fuels, the resulting sulphur dioxide being a major atmospheric pollutant. Combustion of motor fuels causes an added influx of volatile organic compounds (VOC), coupled with carbon dioxide (CO2) and Nox, nitrous oxides. In Malaysia, local and transboundary emissions play very important roles in determining the status of the atmospheric environment (Hassan, Awang and Jaffar, 2006). The major pollutants observed are sulphur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), ozone (O3) and total suspended particulate matter, in particular PM10 (Hassan, Awang and Jaffar, 2006).Industries including power stations, motor vehicles and open burning activities remain the major sources of air pollution in the country. In 2008 a total of 22.971 industrial sources were identified to be subjected to Environmental fictitious character (Clean Air) Regulations, 1978. The breakdown of industrial sources by states is as shown in Figure 6. The highest number of stationary pol lution sources was in Johor (814134%) followed by Selangor (412718%) and Perak (295612.9%). This is perhaps due to the large industrial area in Johor and Selangor that contributed to the pollution. Besides that, both states have a rapid landuse development resulting to the environmental degradation. As to particulate matter, the highest contributor was industries (40%) followed by power stations (25%), motor vehicles (14%) and others (21%) (Figure 7).Source *DOE, Environmental Quality Report 2008.Figure 6 Industrial air pollution sources by state in Malaysia, 2008Motor vehiclesPower stationIndustrialOthers4,557(14%)7,784(25%)12,664(40%)6,667(21%)Source *DOE, Environmental Quality Report 2008.Figure 7 Particulate Matter (PM) emission load by sources (metric tonnes),20084.2.2 Solid and Hazardous WastesGrowing affluence and increasing concentration of population in urban areas have increased the generation and types of solid waste produced. Solid waste management is one of the most i mportant issues of local authorities where much money is spent in the collection and disposal of solid waste (Hassan et. al, 2000). Toxic and hazardous wastes are also one of the major issues in Malaysia. Currently, Malaysia produces about 10000 tonnes of waste either day, equal to 0.8 to 1.5 kg per capita (MGCC, 2006). According to Hassan, Awang and Jaffar, 2006, the amount of solid waste collected in Malaysia is 70 percent of waste generated The remaining 30 percent not collected ends up in illegal dumping sites, or is diverted at source or during collection for recycling purposes. The illegal dumping sites can cause leachate which possibly will contaminate the soil as well as the waterways. The recycling activities amount to only 5% of total waste generated.Manufacturing industry6,830 (38.73%)Sewage treatment plants9,524 (54.01%)Agro-based industry491 (2.78%)Animal farm (Pig farm)788 (4.48%)Solid, toxic and hazardous wastes become pollutants to the water. In 2008, 17,633 water p ollution point sources were recorded. These comprise of sewage treatment plants (9,52454.01%) inclusive 668 cyberspace Pump Stations), manufacturing industries (6,830 38.73%), animal farms (7884.48%) and agro-based industries (4912.78%) as shown in Figure 8 (Department of Environment).Source DOE, Environmental Quality Report 2008.Figure 8 Composition of water pollution sources by sector, 2008Manufacturing industry was in the second place of water pollution sources. This is due to the expanding of industrial estates in the country. Compared to 2007, there are declining in water quality trend of river basins in 2008 (Figure 9). From 94 clean river basins were recorded, it reduce to 79 in 2008. Whereas, the number for both, slightly polluted and polluted river were increased.Figure 9 Riber basins Water Quality Trend based on BOD subindex (1998-2008)Source of Pollution (Activity) Sewage, agrobased manufacturing industries.Pollution Indicator (Parameter) Biochemical Oxygen Demand (BO D)CleanSlightly polluted pollutedSource *DOE, Environmental Quality Report 2008.From all those charts and statistics, there are evidences to shows that industrial estates have become one of the major contributors to environmental pollution in the country. Therefore, there is need for an alternative plan on how to overcome this problem eventhough special requirements and regulation has been put into efforts but still there is declining in environmental quality.4.3 Greenbelt as Environmental Pollution AbatementIn the context of environmental pollution abatement, a greenbelt has been defined as a sideslip of trees of such species, and such a geometry, that when planted around a source, would significantly attenuate the air pollution by intercepting and assimilating the pollutants in a sustainable manner (Ruth and William, 1994). The concept of greenbelt as a source of pollution abatement was recognized initially by three nations The U.S.A., Britain and Kenya (Ruth and William, 1994 Ga reth et al., 1992 Andy, 1991 Parsons, 1990). In reality greenbelts closely always include other vegetation, especially shrubs, which also play some role in capturing pollutants. But trees are the mainstays of greenbelts, and often greenbelt plantation is plain referred as trees eventhough other types of vegetation is also established and nurtured.4.3.1 Air Pollutants Removal by phytologyPlants remove pollutants from the air in three ways(i) engrossment by the leaves,(ii) Deposition of particulate and aerosols on leaf surface, and(iii) Fallout of particulate on the leeward (downwind) side of thevegetation because of the slowing of the air movement(Tewari, 1994 Rawat and Banerjee, 1996).Vegetation acts as CO2 sink and some species have the capacity to utilise air pollutants effectively. Several plants have the capacity to collect the dust suspended in the atmosphere and dilute the concentration of toxic and harmful gases. Trees have been reported to remove air pollutants like hydr ogen fluoride, SO2, and some compounds of photochemical reactions and collect gruelling metals like mercury (Hg) and lead (Pb) from the air (Hill, 1971 Lin, 1976).After absorbing the air pollutants, trees change them to harmless metabolites through various physiological processes. Of course each and every plant cannot be an agent of air pollution control only those which can tolerate pollutants can act as attenuators. All-in-all, increasing vegetation in the cities, towns, and industrial establishments holds great potential to combat air pollution. Substantial evidence is available to support the view that plants in general and trees in particular function as sinks for gaseous pollutants.4.3.1 Soil and Water Pollutants Removal by VegetationSurface water streams are also affected by industrial effluents and organics. near of the treated industrial

Monday, June 3, 2019

Effect of Medicinal Plant Extracts on Alzheimers Disease

Effect of Medicinal Plant Extracts on Alzheimers DiseaseAlzheimers disorder (AD) is a neurodegenerative disease which causes a lethal twist in the structural equity, and a roadblock in the function of mind-set, this even sotually subscriber line the smear to degeneration and shrinkage of spirit, and override the control of brain over other parts of the body, and comes to the final closing remark of the disease- death. Studies d angiotensin converting enzyme on the topic substantiate got corroborated that the disease is not reversible, and the only patch of hope is slowing down its progress. But as the disease advances through mid stage and evolves into severe AD, the take aim of patient becomes pathetic and c be giving becomes more painful. Studies have reported that notable symptoms of AD are seen only after 60 years of age, even though the disease has started before that. Initial symptoms are qualifying of short term recollection- being forgetful about the recent events , and gradually over a period of time patient seems more absent minded about the environment, things which are chemically etched in the long term memory begins to be erased, and the final stage starts pushing the patient into severe AD which is tremendously pathetic.Studies have proved that loss of function of neurons is the cause of AD. A closer ask into the aspect revealed a complex set of events that precede the neuronal degeneration- oxidative stress and imbalance in homeostasis, geological formation of roadblocks in communication, falling apart of integrity and death of neurons. This enabled to go beyond the findings of superficial studies done and supposition developed, and helped to delve much deeper into the inner workings and mechanism of the disease. Hypotheses developed to explain mechanism of AD are amyloid cascade hypothesis, cholinergic hypothesis and tau hypothesis. Amyloid cascade hypothesis says, APP- Amyloid Precursor Protein, a trans membrane protein involved i n main roles of growth, excerpt and repair of nerve cells- is snipped at wrong places by an enzyme called secretase, prima(p) to the formation of amyloid peptides which accumulates to form plaques- amyloid plaques- and bind to synapses blocking the communication channel, lastly causes memory loss. According to cholinergic hypothesis, downward drift in the levels of acetylcholine in brain is the cause for Alzheimers disease. Loss of function of cholinergic neurons was found in Alzheimers disease patients. Shift in the level of acetylcholine happens overdue to the lack of two enzymes involved in synthesis and breaking down of acetylcholine. This pass on lead to loss of function of neurons brains functionality falls apart, and eventually leads to symptoms of Alzheimers disease. Tau hypothesis approaches the problem in other perspective, tau protein- a protein associated with microtubules in nerve cells- gets hyperphosphorylated, this enables cross linking among tau protein units, and they covert off from being attached to the microtubules. This causes loss of structural integrity of nerve cells, and they collapse and clump to form tangles- neurofibrillary tangles. Studies conducted focusing on the inner workings of these hypothesis have found that oxidative stress is the reason that enhances plaque and tangle formation, repair mechanisms in cells are unable to solve the situation as the oligomer formation and cross linking are predominantly made by non peptide bonds. In another study, amyloid peptides have shown close relation with some causes of mad cow disease. Studies think to genetics of AD have found the link between APOE gene on chromosome 21 and the disease. APOE gene codes for apolipoprotein, and one among its functions is breaking down of APP. APOE has variants, APOE4 is the one which codes for less active protein whose capacity to break down APP is sluggish. People with this variant gene are more tend to develop AD in afterwards stages of life , and any ab approach patternity related to chromosome 21 also results in AD over a period of time.To know more about the mechanism of disease and its attachment to oxidative stress, further studies have done from different angles, and all the studies have come to a common point, the findings from all the studies stitched together gave a complex and elaborate picture about the mechanism of the disease. Free radical damage leads to oxidization of products in cell. Oxidation leads to new end products of glycation, nitration, lipid peroxidation, and oxidation of nucleic acids. These new end products chemically modify other proteins and compartments inside the cell. Oxidized derivatives impede with the channel of trace elements, and imbalances their homeostasis, and enables proteins like tau to form non peptide cross linking. In receipt to changes cell up the levels of heme oxygenase-1 (HO-1)- an antioxidant enzyme to mitigate the bad effects from free radical damage- but rapid heapi ng up of neurotoxic substances goes beyond control leading to severe imbalances, blockage of communication channels, and eventually death of neuron. Since mitochondria is the main source of free radicals and oxidative precursors. Certain deletions in mtDNA resulted in change in normal levels and rates of metabolism and production of free radicals. Free radicals formed in mitochondria are short lived and they do not have the ability to cross membrane and reach cytol to cause damage, this led studies in a new direction and found free radicals- OH from cytoplasm- can attack guanidine in RNAs in cytoplasm and this both can cross the membrane and reach into mitochondria, and cause imbalance and production of more stable H2O2 radicals which can come to cytoplasm and react with the channel of trace elements, and starts the primary events for the major causes for AD to come into being. AD starts at neocortex area of brain, and as the neurons die and rupture, the neurotoxic substances- plaq ues, free radicals, tangles, etc. spread the nearby nerve cells, and the cycle goes on and gradually covers the brain and makes it slip out of its normal being.Oxidative stress in brain leads to degeneration of neurons, which eventually leads to dementia, and Alzheimers disease (AD). This oxidative stress in brain can be slowed down or reversed- to a small extent- using drugs to treat AD or using antioxidant capacity of some medicinal plant lifes. In this study rats were arranged into seven groups, and different groups were treat with different plant extracts and rivastigmine. AD was kick in forth using atomic number 13 chloride- rats were given atomic number 13 chloride for one month, and the dosage was 17mg/kg of body weight. One group was kept as control- healthy control and another group as AD-induced. Rivastigmine was given to group 3. Group 4 and 5 were treated with extracts of a medicinal plant- Salvia triloba and group 6 and 7 were treated with extract made from Pipe r nigrum. The rats were given drug and extracts for three months. At the end of three months duration biochemical assays and histopathology was done to examine the changes happened to the brains. The following things were canvas for in serum malondialdehyde, total antioxidant capacity and nitric oxide, and level of superoxide dismutase were checked in erythrocytes. Acetylcholine and acetylcholine esterase levels were checked in brain samples and another group of brain samples were given for histopathology. From the results, the rats which were treated with Piper nigrum extract and rivastigmine showed increase in brain Ach, and serum TAC and SOD and a satisfying decrease in brain AchE, and serum MDA and NO. The rats which were treated with extract of Salvia triloba showed even better result in subduing the oxidative stress to a certain limit.Antioxidant capacity of plants was used to bring down the effects of oxidative stress in brain. Here, the effect of the extract made from Bosw ellia serrata is compared with rivastigmine on rats with AD- induced by oral administration of aluminum chloride. Ninety male rats were used in the study. They were made into nine groups. Group 1 was kept as healthy control, group 2 was given with aluminum chloride for four weeks, and group 3 was treated with rivastigmine, group 4 and 5 were treated with two different concentrations of plant extract made from Boswellia serrata. Groups 3 to 5 were treated with a combination of aluminum chloride and other things to check the ability of extract and drugs to protect the brain from the stress. Group 6 was given with body of water after inducing AD. Group 7 was given with rivastigmine, and group 8 and 9 were given with two different concentrations of plant extract- this was done for twelve weeks. cognitive tests were done at the beginning of each new stage of the study. At the end of the duration of the study, the brain samples were subjected to biochemical assays and histopathology. Fro m the results, B.serrata has significant ability to reduce the oxidative stress in brain, and higher window glass if the extract showed better effect- bringing down the severity of oxidative stress damage.Bacopa monnieri is another plant used to trim down the effects of AD. This plant is used since ancient times for improving intelligence, and in this study its ability to protect against AD is checked. Alcoholic extracts of the plant was made for the study. AD was induced using ethylcholine aziridinium ion (AF64A)- administered intracerebroventricular way bilaterally. Plant extract was given to the rats two weeks before and one week after the administration of AF64A. rats were subjected to cognitive tests. Rats treated with the plant extract cleared the tests in less time. Histopathology results showed, low dose of the plant extract brought down the phase of damage in brain- reduction of neurons density. Low dose showed better result compared to the medium and high dose. The stud y has not revealed the mechanism of action of the plant extract, but it showed the scope for a further study on the same.Targeted drug delivery to brain in case of Alzheimers disease is more complex process due to many factors like blood brain barrier and actions of plasma proteins. But nanoparticles are used for targeted drug delivery, and this is again affected by physiochemical properties of Nanoparticles in different surfactants, stability of nanoparticles and organic coating or capping agent on nanoparticles. Blood brain barrier is a homeostatic defense mechanism used by brain to screen out pathogens and unwelcome materials from entering brain. The barrier screens the solutes biochemically, physicochemically and structurally at the periphery. There are times when blood brain barrier breaks down due to certain infections or due to any physical reason, and this makes it skew from its usual nature- highly selectively permeable. Studies have been conducted to find how nanoparticle s are treated at blood brain barrier. In a study, nanoparticles were made by warm microemulsion precursors, and the nanoparticles were radiolabelled by entrapment. Then an in situ study was conducted to check how nanoparticles cross the blood brain barrier. From the study it was concluded that endocytosis or transcytosis as possible mechanism for the transport across the barrier- more studies are yet to be conducted. Studies have shown that clioquinol- a quinoline derivative- can solubilize amyloid plaques in vitro and this could prevent compendium of amyloid plaques in Alzheimers disease transgenic mice- an in vivo study. Clioquinol has shown its ability to dissolve plaques which are induced by Zn and Cu ions- NMR studies have shown that clioquinol can remove bound Cu ions from amyloid plaques. The study conducted has overlooked the toxicity part of clioquinol- though clioquinol has many side effects attached to it at high doses. It has shown in the later part of the study that clioquinol coupled with nanoparticles could easily cross the blood brain barrier- higher degree of uptake by brain. So, clioquinol-nanoparticle delivery system is suggested to be considered as one among the models for treating Alzheimers disease by targeted drug delivery. Even though using nanoparticles are considered for drug delivery, there are studies showing the side effects, and doses. In a study- toxicity of silver nanoparticles- it was found that exposure to more than 125mg/kg of silver nanoparticles will lead to liver damage due to toxicity.In a study curcumin nanoparticle formulation was used to test its effect on Alzheimers disease in mice. Nanocurcumin was synthesized and orally given to the mice for twelve days. Memory tests were done before starting every new stage of the experiment. Results have shown that mice treated with nanocurcumin could clear the cognitive tests- significant improvements were observed.

Sunday, June 2, 2019

The Problem of Pornography Essay -- Argumentative Essay, Censorship 201

In the United States some unity has to be eighteen years old before they can buy pornography, further just because they have to be eighteen to buy it doesnt mean they have to be eighteen to look at it. Everywhere around the Internet one may stumble upon pornography where anyone, including children, may look at it. vulgarismography is not something to be proud of and is not something that our children should be able to see indiscriminately on the Internet or in a store at a young age. In Susan Brownmillers essay, Lets Put Porn Back in the Closet, she argues that pornography represents hatred of women, that pornographys intent is to humiliate, degrade, and dehumanize the female body for the purpose of erotic stimulation and pleasure, which I altogether agree with. (Brownmiller 53.) Women that respect themselves or other women would never pose for any type of pornography. People should never look at a woman as if they are just an object in a magazine or movie. Women should be respec ted and so should their privacy. When I was growing up, pornography was not something peopl...

Saturday, June 1, 2019

Paranoid Schizophrenia: They’re Out To Get Me Essay examples -- Menta

Paranoid Schizophrenia Theyre Out To Get Me establishmentParanoid Schizophrenia is a serious psychotic disturbance that impairs a persons perception of trueity, causing the mind to lose contact with the real world. This disorder greatly affects ones ability to negotiate the activities of everyday life, such as school, work, or social situations. In 1898, Emil Kraepelin was to the first to provide info regarding schizophrenia naming it dementia praecox, and defining it as a psychosis with an early onset of intellectual deterioration (Schiffman & Walker, 1998). Ten years later, a Swiss psychiatrist, Eugen Bluler renamed the disorder using a combination of the Greek words skhizein and phren meaning split mind (Barlow & Durand, 2011). He believed the unusual behaviors were a split from the basic functions of personality and reality. Today, there are misconceptions about the term schizophrenia in which society confuses a split mind with a split personality. The broad definitio n of schizophrenia continues to be researched and narrowed into subtypes with specific presenting characteristics. Paranoid schizophrenia is one of the five major sub-types tilted in the Fourth Edition of the Diagnostic Statistical Manual of Mental Disorders Text-Revised (DSM-IV-TR) with the list continuing to expand as the criteria identifies specific related symptoms or behaviors (American Psychiatric Association, 2000). Although this disorder only afflicts 1% of the total population of the United States, this amounts to over 3 million people living with the disorder. DiagnosisDiagnosis of this syndrome typically occurs in late adolescence through early adulthood with the onset of behaviors marking deterioration in the abilit... .... (2010). The history of mental illness From skull drills to happy pills. Student Pulse, 02(09), 1-4. Retrieved from http//www.studentpulse.com/articles/283/the-history-of-mental-illness-from-skull-drills-to-happy-pillsMaguire, G. A. (2002). Comp rehensive understanding of schizophrenia and its treatment. American Journal of Health-System Pharmacists, 59(5), 4-11. doi 1079-2082/02/0901Maguire, National make of Health. National Institute of Health, National Institute of Mental Health. (2009). Schizophrenia (09-3517). Retrieved from U.S. Department of Health and Human Services website http//www.nimh.nih.gov/health/publications/schizophrenia/schizophrenia-booket-2009.pdfSchiffman, J. & Walker, E. F. (1998). Schizophrenia. In H. Friedman (Ed.) The Disorders Specialty Articles from the Encyclopedia of Mental Health. academic Press New York.

Friday, May 31, 2019

Magical Realism and Psychology Essay example -- Magical Realism Litera

witching(prenominal) Realism and PsychologyMagical realism was first-year used by the art critic Franz Roh to designate the pictorial output of the Postexpressionist period, beginning around 1925 (Leal 120). Later, this term was applied to forms of literature. This type of literature contains characteristics much(prenominal) as real and unreal elements, no hesitation, and hidden meanings. Given these and other characteristics, it is easy to see that magical realism can be applied to things outside of literature, such as psychology.In magical realism stories, the places and things are real and unreal at the same time. Luis Leal states that what used to be called empirical reality, or the world, seems to swallow move around more and more unreal, and what has long been regarded as unreal is more and more turned to or studied as the only true or another as valid reality (153). Brooke-Rose says that the inversion of real/unreal is perfectly logical (qtd. in Leal 153). This quote see ms to coincide with Faris statement that the wonders are recounted largely without comment, in a matter-of-fact way, accepted - presumably - as a child would accept them, without undue questioning or reflection (177). From class discussion, I have plant that there are also many ways to interpret the meaning of magical realism stories.A dream is a sequence of moving images, base on a significant thought which may be either conscious or unconscious (Hearne and Melbourne 42). Anthony Stevens says, from the standpoint of dream psychology, the most extraordinary dexterity of the human psyche is its genius for fabricating images (176). He states an image becomes a symbol when it is endowed with meaning (176). According to Stevens, Dream interpretation...is an art,... ...reams. Magical realism has probably become popular due to its ability to transport the reader into a new world and make him or her forget about reality.Works CitedBorges, Jorge Luis. The Circular Ruins. A Hammock Benea th the Mangoes. Ed. Thomas Colchie, N.Y. Plume Printing, 1991. 25-29.Faris, Wendy B. Scheherazades Children Magical Realism and Postmodern Fiction. Magical Realism Theory, History, Community. Ed. Lois Parkison Zamora and Wendy B. Faris. Durham Duke U.P., 1995. 163-190.Hearne, Keith and David Melbourne. Understanding Dreams. London New Holland Publishers, 1999.Leal, Luis. Magical Realism in Spanish American Literature. Magical Realism Theory, History, Community. Ed. Lois Parkison Zamora and Wendy B. Faris. Durham Duke U.P., 1995. 119-124.Stevens, Anthony. Private Myths Dreams and Dreaming. Cambridge Harrard U.P., 1995.

Thursday, May 30, 2019

The Causes and Effects of the Iranian Revolution Religiously and Politi

A revolution is a mass reason that intends to violently transform the old government into a new political system. The Iranian Revolution, which began in 1979 after years of climax, was an uprising against the Shahs autocratic convention resulting in much religious and political change. Shah Muhammad Reza Pahlavi do efforts to remove Islamic values and create a secular rule and westernize Iran through his White Revolution. In addition, his tight dictatorial rule and attempts at military expansion felt threatening to the people, who desired a fairer political rule immensely influenced by Islam. Afterwards, governmental affairs became extremely influenced by Islamic traditions and law which created changes religiously and politically for years to come. Although the Iranian Revolution was both a political and religious impulsion in that it resulted in major shifts in government structure from an autocracy to a republic and that Islamic beliefs were fought to be preserved, it was more a religious act in that the primary goal of the people was to preserve traditional ideology and in that the government became a theocracy intertwined with religious laws and desires of the people.Although the Iranian Revolution was caused by cabal of political and religious motivations and ideas, the desires of the people supporting the movement were more dominantly religious ideas that were wished to be imposed in society and in a new government. The Shah, or king, of Iran at the time was Muhammad Reza Pahlavi, who had developed relations with nations in western world, specifically with the United States. The United States supported the White Revolution, which was a series of social reformations the Shah made to remove Islamic v... ...e were these political results mostly noticed were the religious changes.Though the White Revolutions efforts were made to remove Islamic values, create a secular rule and westernize Iran by Shah Muhammad Reza Pahlavi, the people desired a fairer governmental rule immensely influenced by Islam. The Shahs tight dictatorial rule and military expansion attempts were viewed as threats as well and resulted in the overthrowing of the government to create religious and political change. Although the Iranian Revolution was a religious and political movement that ended an oppressive rule to established a republic and which was fought to maintain Islamic beliefs, it was more a religious movement in that the movement was a result of desires to create a society influenced religiously and politically and that the result was a republic based on Islamic values and law.

The Role of Technology in Warfare Essay -- Exploratory Essays Research

History does not teach that better technology necessarily leads to victory. or else victory goes to the commander who uses technology better, or who can deny the enemy his technology. Office of the Chief of Naval Operations (qtd. in Schwartau 540) As the future of war becomes more sophisticated, what will be the host technology of tomorrow? The North Atlantic Treaty Organization, NATO, believes that there are three possible answers to that question nuclear warfare, biological/chemical warfare, or cyber warfare. While nuclear and biological warfare is conducted on a battlefield, cyber warfare operates via the Internet and computers. All of these weapons have the same pestilential potential, but the circumstances surrounding their uses and aftereffects are very different. With what new technology will a commander in World War III fend for? Military commanders of the future will make greater use of state-of-the-art computer technology to fight wars, making the usage of conventional weapons obsolete.Since the beginning of military history, the commander who made the best use of technology always won. No matter if it was the arrows and tomahawks of the Native Americans against the guns and cannons of the European settlers, or the order given by president desolate Truman to drop two nuclear bombs on Japan, the army with the preeminent technology always came out on top. A short time ago, an American airplane dropped one bomb on Hiroshima and destroyed its usefulness to the enemy. That bomb has more power than 20,000 tons of TNT (qtd. in Hiroshima). This quote by Harry Truman describes the power of the first option, nuclear warfare. German and Austrian scientists, working for Adolf Hitler, created plans for a nuclear weap... .... 2000. Works Consulted Clinton, William Jefferson. Address. Address concerning Computer Security. White House, Washington, DC. 7 January 2000. *Cohen, Fred. . 6 Feb. 2000. email to the Author. 6 Feb. 2000. Douglass Jr., Joseph D. Ch emical and Biological Warfare Unmasked. 2 Nov. 1995. InfoManage. 18 January 2000 Haeni, Reto. Infowar. January 1997 16 pp. Icove, David, Karl Seger, and William VonStorch. Computer Crime A Crimefighters Handbook. Sebastopol OReilly & Associates, Inc., 1995. Stocker, Gerfried, and Christine Schpf. Infowar. Austria SpringerWeienNewYork, 1998. unify States. President of the United States. National Plan for Information Systems Protection. Washington 2000.